SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e782caee37358587e418f2c722db2022bbe26c2f8c1f678a1c8568c8f1a65c' 
  AND token = 'fHJrRnhUXdKazBDsxyU6DCChwpfUkaqf5CfYcLKZY94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}