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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd42389ae229a7ac972f8c9aaa346de2a204e175f571c9238874f92c4a2d0dd6a' 
  AND token = 'Tc+0qg72Woo1qiE0dOKOwsybFeCR7OHem9E46X70YtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}