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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f67c694a75f90fff9c543b9c5c2c456d2c6aa37233d2132d8cb37a211b1b51c' 
  AND token = '1hmEeimcuapPGQ3GHLXH8uDoFOl3C90G2jaUnfP1YXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}