SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b7c35ca81f97ac49d0c30ba2a6dc6dadc7377b493f573fe8ce97297dc7b886' 
  AND token = '5vL/8yM5aD1Bd5/nNmVQPTLIEqQ5jnoZqdfOSWa6hoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}