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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fd661b2d072a9146c38a8fe8cf96040c7348bd3e62f5a63f14427d8992ecb23' 
  AND token = 'JaYIcgXiSBN1osHJ3RUCJ88aIi8o672Kd2rTSo22Z/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}