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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e3dba7aea2967a3e0052c09c1079afedc4f334d3737189f5b68f1101fa7d50' 
  AND token = 'SHtDnwKCChQsQsmso+ZovB1BR953b4+VZ51ssPpnlmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}