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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2263ec55a18cf6315894ed5691212cd63d01b065014d97865a70c471ef1df15a' 
  AND token = 'L+8PpkCJbfzLZNGoF/6JNUXXbnBcao4wU//uf/hzS60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}