SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05d67ef54ce78c78a29bc444a9811895173e982064b98fb2c8c915692421a74' 
  AND token = 'BtUb8Iu+q0uqPFPwXNPaTPXt9uknBSbiilLk2bLnOJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}