SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '044b033297ba84e9fb2506c30f4317f5da817c985a0a9fb11c6ea8ce4714c22a' 
  AND token = 'jc2aJiQL/x4GbLY3frM2/mZqbztcbxGxU18tqIESvws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}