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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8ae7b84a7a9d859c962afa3e3a692278a18c66d64bc8119c357a2e79b384913' 
  AND token = 'R3F+YjaUdeOGSYUkQ2PtPSI1i1LqQz26hA7XR4MHOpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}