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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04dfd1dffe21fe4359ef94ddf4df5fa6400c057a698e3f9ab6a211a510d08eaf' 
  AND token = '42cUxQ8z+UsVgx4gJWQu4vnrZcUnuZ5xjfL9qCrkltY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}