SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c83842cb70b04b3558b521ad00edba975c3fdcfddc2361c63222f5499d0486f' 
  AND token = 'uOF3jgXYgp4Bdd1fmc8FxHLivcb287a9IHTLvwVy858=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}