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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49081854b733bab5465dc2484e4672f4b8e6936f34fe2177b6600e5b4fab8809' 
  AND token = 'diVWGxtf8yjszFA07yn+Vy/6wKErcVzs96kJzLTHy8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}