SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edf80023bc98f9e62da58dcbf05f8835075e96490b007d752133a67f009efa54' 
  AND token = 'oLjX03Alz5Vl2vfIKZNSzup9/hp4yGhwdANTzBJxkuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}