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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd541b1765839f5e45b39c0a3709a6a186ab8d9d66a77178b402d1106f701526b' 
  AND token = 'cPqKW6ZjfLs369x/p2s9XLedJlpczDFeRWzDz0ggAXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}