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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781d8040b7d799f42a7a4e5c616d80f236ee1a3b2bbf54feb3a71491d6b9cbb1' 
  AND token = 'awxmK2ZucELdO0TmiXKGoUik/4VFltSB07jwl8D65oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}