SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '916d163dc7c66547207f4b032976291fe67f5ab09b1cd497687a4a57ed5a4d9e' 
  AND token = 'R3eGKzDhn1fkEJqiG42O4Sp5aGpxmodXQVpo5sDjxBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}