SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d7375983a210524d55f7bc610be72bc5ec06dd92e44cf7020f9fd07be8d0b10' 
  AND token = 'o7VOiDufKd4KLuX6Eq+yHIFkk1u7UEhGaNs2Pq1xpjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}