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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2192fe4a232da2bd4cc9ae9151004b12209a3ec0c864f93d39c21690dc975fbb' 
  AND token = 'ASHs7XDAqTuHhd0WuxZKZXGYhGhkCSij5kle+bHqJ7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}