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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b77b8ae1d20e57f1c096e213b3e4254511cdef57835f3423060f80084b062e' 
  AND token = '2DxEr+YF6EvyHCpM3LtfqbN4BMX/S7t3qT2ZBCT+F+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}