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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c4203344b5ac364bb694235e87d31255454d347c749f47d0f06446c514191c' 
  AND token = 'VsNDNp+H1w/tRCZdfNIetp+/h8pjH6LsONkW8qkDAyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}