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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8623590425f851fd267e650f80f80eedfee2a7d93c9dda2eab00654ad4f1b734' 
  AND token = 'Xsg505aEzBRxyRz7Wo6qELq0/jjaZs6q8IyfTgZCn4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}