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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b184ca3e896cb7279f43f782c74ad77fa420b258fe57bfd09ce8f9243c1d01b' 
  AND token = 'P7YS3fpy4naDc67ZRxwZ8GBIv6U+zmGTwZG+hfe2SGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}