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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf22c2756c8f00e77c140a7527f145ea1d09614f3af6f2e63c66898c47eba27a' 
  AND token = 'AUAWLttV8MH5Emp/dQW05JinB6sqOXkzMbTiLwXkdlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}