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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22f77cef50684a27701398db9c4dbd663da6355aa0e194c5d6a2dc3d76d76fa' 
  AND token = 'CMVcW7HwwK7SEJDY9jyMMM8AA4dvGFSUtnS00G2ecnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}