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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2130e7f70391cccb0cad4c19576bc678776a16d519a526cee97944cefd1f0363' 
  AND token = 'O1ZWCP9zKHrFNBVd85p5YFEETSJEdZP4sD6qywP4SOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}