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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2083c8de6757afde7d6a3c321d3a9e7fa350e7ac689071df2038ee2b259971d5' 
  AND token = 'O0GfKQI6o5L2vuqmTBa4z3vsI+zy8tjtVEZ/PGI6t7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}