SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f74714ddc6c13998a4ddc16b1b97e33680780077da1ad733edf9de18193423cb' 
  AND token = 'TcKlBsmB6izW6PY1W80kzLbOdW+Ph+Po5KJiIZgQ0PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}