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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be2d68ee68ec4f928dec63ebd942813b5529216fddd50ee780807da62f2c596' 
  AND token = '4pjl6FGLsHrRGTEClqBwFijrYlRl0A+oz9mWebpqzqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}