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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18e8b679c86b5ead457716c9b32dce6eb0c3c75d807eaa37d195620e9317224' 
  AND token = 'UZzpU2p6ZRNucNP+8UILLRbBI97a/nwVzrDlXDR26K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}