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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f510438af96663a00cc7c1e10ec43ece3e3629b9abd29b22c8daea40c8f8363' 
  AND token = 'kygudGE4GqlD212eTAbvdP61XsUYeF/t7OqcTMWLWVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}