SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '750ca714b8f2c15e0a62c0ff689da34745863fe49e6001e9d0bdc64c4c078da5' 
  AND token = 'Eibq5FZE/JRahh6TBWMnzDhxZj4+i6ifuLwwrm6c2yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}