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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed357ce05d3d53a9f839dc0322ffe084e3dc7ecb2cc86e743f040831759c1c9' 
  AND token = '5kmVIEIn1KTDiOrh5gZSt/h28td9Rh0VxJWFNZa8W/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}