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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a9a0edb01bfacd4099cf00cec8620a2184d329bbe7d4531f10895263e8dd99' 
  AND token = 'Ob32q618Xdz98P/znSqMnEM+3d1Ap7GR9SdlVIfzsQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}