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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74973590e15b106a11bd540eba331b5cb52fdf8f3d729dd2be07f169d4fe795e' 
  AND token = '77+7dF9Z2go7DgtZQUnVl02KB2+33F1rPAxRLQZYm20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}