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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e9347deed2500137f2c161c3698814e2df2dabd939bb46086af95695a90b034' 
  AND token = 'fCLrkryA0rnMJkzEOA6CNahtJ+HZ3TOAfUQZSilWCvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}