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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b842205d596699cc6afce05136b9e2acaf6c875c3ea22cd874f2832590f507' 
  AND token = 'zI/m1xgVRtbopmcHz6N6mWl15r85pwaHbrfpDEzVERo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}