SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '432b2c1cfa4c73078d253c6353cf98f86b494459266eae8c11b218e2d7d722c5' 
  AND token = 'abdK3Mnj28uj5gHHf/8//sdLkiqTluCa+qW0JNG6pn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}