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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8c6e5dc9f54c8366571f96e9490ca782e36bf4ea1f75ab0b4c1901051b0382' 
  AND token = '3DqAR2Sq/IFqs4ApAHBLB9jQzKeNx30yV5Il13ElJxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}