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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e17c73d8756173fbebe9b6143433a1b820e8021851427440b2cb021f191ad7' 
  AND token = '6lMc/PgJnmgivVuvo7SMEG5gXXw7ENjfFLjfMYEOn6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}