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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f12848086e8c0b0c84ea73d94aede53bec437931add4aa0e5c3a1042a012d334' 
  AND token = 'ihnFPqazGa/cOV1yTw0HZnbFyVDWVHpz8/2dW3WY4eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}