SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2598c0bac260288bb34b8649927ed6e80c4df5b654364fa29f68019c0c13a821' 
  AND token = 'BXPKW85aTiDXKygfl3u4KZplK7xlMUiuNSBENk1i2Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}