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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa01ed0a45391e01d16384d3d207cd181a254597d75e9d02235702f70b05d908' 
  AND token = 'Zu86gLFBXBK6TCGG2l/F2VgOXOLsI5XdyPXXJLZ1PaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}