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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccba29a92f447978bc93c96d7efb86cf24b92b2824bfb66796d1d7862a454af2' 
  AND token = '8WyWA1Gc1Z0+EYbZGdrf+byAAN6QtsVde9hkR7uOyQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}