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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd52e76fa7bb734007bfe22502c05956d161f92d0d3619b2f5ba46c5e2de2d242' 
  AND token = 'NAthHAFnSfkeme4nZtipF7QJq3GT3Yz/73mRC/zaK2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}