SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c3c08dca645115928905c06380a88b671aeb76885a5fd26fa4a13e523981248' 
  AND token = 'o+rR2WqN9a67yKMDx8YAxEUR7iwKlwnI0kwSI9ppxOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}