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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff7ea981e05478351691635bf0aea1cdd6c854034597b5f95a3c7aedd4859b6' 
  AND token = 'vNKiHd3LndAELsRPhhfBuIukIjEMPVguAqW1Ou3H8Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}