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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07a9d5633930c6ce59a4cccdc4c7241083a49a41bcd29e0355d1a6b1bbfe548f' 
  AND token = 'xQRq7fhWgEKHSkvFUXQzH4ZMV5qsdcHQJqInhrIlDp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}