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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e78f9f16a10764849003fd37993e9b2514b8c1eadc95b0d3a950d37c0da186' 
  AND token = 'lV2WPT++ScY/94Uid8qCykc1g7RIFCer9gVIQoGpvnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}