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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1bd3c675b534e97d3c5dff6dd72344f41dce24a1ecfa668119e80abcb8b340c' 
  AND token = 'iZw4pAnsZz3yRBp9+yrWpW/QYtUPAPvN+g9yWrdlOBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}